Acute retinal necrosis following recombinant subunit varicella-zoster virus vaccine

Acute Retinal Necrosis Caused by the Zoster Vaccine Virus

We report acute retinal necrosis caused by the vaccine Oka strain following immunization of a 78-year-old woman with live zoster vaccine. Whole genome sequencing confirmed the ocular vOka strain to be derived from the vaccine and excluded the presence of new mutations or recombination with wild-type Varicella zoster virus.

Variable R1 region in varicella zoster virus in fulminant type of acute retinal necrosis syndrome.

BACKGROUND/AIMS Varicella zoster virus (VZV) is a causative agent in acute retinal necrosis (ARN) syndrome. However, in spite of aggressive antiviral therapy, clinical characteristics among patients have varied. Different viral strains were examined to determine their respective role in producing clinical characteristics. The viral strains were also compared with those of previously reported on...

Acute retinal necrosis secondary to varicella zoster virus in an immunosuppressed post-kidney transplant patient.

Acute retinal necrosis following contralateral herpes zoster ophthalmicus.

BACKGROUND A case report of contralateral acute retinal necrosis (ARN) following herpes zoster ophthalmicus. CASE A 61-year-old male patient developed iridocyclitis and well-demarcated creamy-white retinal lesions at the nasal periphery in the right eye 1 month after herpes zoster ophthalmicus in the left eye. The patient had undergone surgery for primary lung cancer, and had subsequent intra...

Herpes zoster caused by vaccine-strain varicella zoster virus in an immunocompetent recipient of zoster vaccine.

We report the first laboratory-documented case of herpes zoster caused by the attenuated varicella zoster virus (VZV) contained in Zostavax in a 68-year-old immunocompetent adult with strong evidence of prior wild-type VZV infection. The complete genome sequence of the isolate revealed that the strain carried 15 of 42 (36%) recognized varicella vaccine-associated single-nucleotide polymorphisms...